FreeBody

  • Direct measurement of the forces that occur within our muscles and joints is incredibly invasive and difficult to achieve in vivo. Musculoskeletal models provide a way to determine muscle and joint reaction forces from kinematics and kinetics of motion. FreeBody is a segment-based musculoskeletal model of the lower limb.We can provide it in two ways:

    1. A Windows application and Matlab code that may be used as given, or as a framework for the development of your own bespoke models.
    2. Fully-open source code written in C plus the Matlab code as above.

  • Ziyun Ding, Department of Bioengineering, Imperial College London, London, UK
    Daniel Cleather, School of Sport, Health and Applied Sciences, St. Mary's University, Twickenham, UK
    Anthony Bull, Department of Bioengineering, Imperial College London, London, UK
  • Key publications Software version Data
    D. Toderita, D. P. Henson, C. Klemt, Z. Ding and A. M. J. Bull (2021) An Anatomical Atlas-Based Scaling Study for Quantifying Muscle and Hip Joint Contact Forces in Above and Through-Knee Amputees Using Validated Musculoskeletal Modelling. IEEE Transactions on Biomedical Engineering (2021). doi:10.1109/TBME.2021.3075041 FreeBody 2.1 Lower limb amputee musculoskeletal anatomy atlas
    Ding, Z., Tsang, C.K., K.Y. Nolte, D., Kedgley, A.E., & Bull, A.M.J. (2019) Improving musculoskeletal model scaling using an anatomical atlas: the importance of gender and anthropometric similarity to quantify joint reaction forces. IEEE Transactions on Biomedical Engineering (2019). doi:10.1109/TBME.2019.2905956 FreeBody 2.1 Lower limb musculoskeletal anatomy atlas
    Ding, Z., Nolte, D., Tsang, C. K., Cleather, D. J., Kedgley, A. E., & Bull, A.M. (2015) In vivo knee contact force prediction using patient-specific musculoskeletal geometry in a segment-based computational model. Journal of Biomechanical Engineering, 138(2). doi: 10.1115/1.4032412 FreeBody 2.1 1. Patient-specific anatomical datasets
    2. Kinematics and ground reaction force data during activities of daily living, including gait, rising from a chair and squatting
    Cleather, D. J., & Bull, A. M. J. (2015). The development of a segment-based musculoskeletal model of the lower limb: Introducing FreeBody. Royal Society Open Science, 2, 140449. doi: 10.1098/rsos.140449 FreeBody 1.0 1. Generic anatomical dataset
    2. Kinematics and ground reaction force data during jumping
    Cleather, D. J., & Bull, A. M. J. (2011). An optimization-based simultaneous approach to the determination of muscular, ligamentous, and joint contact forces provides insight into musculoligamentous interaction. Annals of Biomedical Engineering, 39, 1925-1934. doi: 10.1007/s10439-011-0303-8 Imperial College Lower Limb Model (ICLLM)  
    Cleather, D. J., Goodwin, J. E., & Bull, A. M. J. (2011). An optimization approach to inverse dynamics provides insight as to the function of the biarticular muscles during vertical jumping. Annals of Biomedical Engineering, 39, 147-160. doi: 10.1007/s10439-010-0161-9 Imperial College Lower Limb Model (ICLLM)  
    Cleather, D. J., & Bull, A. M. J. (2010). Lower extremity musculoskeletal geometry affects the calculation of patellofemoral forces in vertical jumping and weightlifting. Proceedings of the Institution of Mechanical Engineers: Part H: Journal of Engineering in Medicine, 224, 1073-1083. doi: 10.1243/09544119JEIM731 Imperial College Lower Limb Model (ICLLM)  

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    PLEASE READ THE AGREEMENT CAREFULLY BEFORE DOWNLOADING THE SOFTWARE. BY EXERCISING THE OPTION TO DOWNLOAD THE SOFTWARE YOU AGREE TO BE BOUND BY THE TERMS OF THE AGREEMENT.

    SOFTWARE LICENCE AGREEMENT
    1. Ownership and Licence. Your non-exclusive rights to use the software downloaded to your computer and all other copies that you are authorised by this Agreement to make (the “Software”) are specified in this Agreement, and we (or our licensors) retain all rights including but not limited to all copyright and other intellectual property rights, anywhere in the world, in the Software not expressly granted to you in this Agreement.

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    (b) You may use the Software solely for non-commercial, academic research purposes and only in accordance with the terms of this Agreement. You may not use the Software for, or in relation to, patient management or in, or in relation to, clinical trials.

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    3. Warranty Disclaimer

    (a) Disclaimer. The Software has been developed for research purposes only and is not a clinical tool. You acknowledge that we are providing the Software to you under this licence agreement free of charge and on condition that the disclaimer set out below shall apply. We do not warrant that the Software will meet your requirements or that its operation will be uninterrupted or error-free. You acknowledge that you have reviewed and evaluated the Software to determine that it meets your needs and that you assume all responsibility and liability for determining the suitability of the Software as fit for your particular purposes and requirements. Subject to Clause 3(b), we exclude and expressly disclaim all express and implied representations, warranties, conditions and terms not stated herein (including the implied conditions or warranties of satisfactory quality, merchantable quality, merchantability and fitness for purpose).

    (b) Savings. Some jurisdictions may imply warranties, conditions or terms or impose obligations upon us which cannot, in whole or in part, be excluded, restricted or modified or otherwise do not allow the exclusion of implied warranties, conditions or terms, in which case the above warranty disclaimer and exclusion will only apply to you to the extent permitted in the relevant jurisdiction and does not in any event exclude any implied warranties, conditions or terms which may not under applicable law be excluded.

    4. Limitation of Liability

    (a) You acknowledge that we are providing the Software to you under this licence agreement free of charge and on condition that the limitation of liability set out below shall apply. Accordingly, subject to Clause 4(b), we exclude all liability whether in contract, tort, negligence or otherwise, in respect of the Software and/or any related documentation provided to you by us including, but not limited to, liability for loss or corruption of data, loss of contracts, loss of income, loss of profits, loss of cover and any consequential or indirect loss or damage of any kind arising out of or in connection with this licence agreement, however caused. This exclusion shall apply even if we have been advised of the possibility of such loss or damage.

    (b) Nothing in this Agreement shall have the effect of excluding or limiting our liability for death or personal injury caused by our own negligence. This licence does not permit you to use the Software for, or in relation to, patient management or in, or in relation to, clinical trials.

    (c) Some jurisdictions do not allow these limitations or exclusions either wholly or in part, and, to that extent, they may not apply to you. Nothing in this licence agreement will affect your statutory rights or other relevant statutory provisions which cannot be excluded, restricted or modified, and its terms and conditions must be read and construed subject to any such statutory rights and/or provisions.

    5. Confidentiality. You agree not to disclose any confidential information provided to you by us pursuant to this Agreement to any third party without our prior written consent. The obligations in this Clause 5 shall survive the termination of this Agreement for any reason.

    6. Termination.

    (a) We may terminate this licence agreement and your right to use the Software at any time with immediate effect upon written notice to you.

    (b) This licence agreement and your right to use the Software automatically terminate if you:

    (i) fail to comply with any provisions of this Agreement; or

    (ii) destroy the copies of the Software in your possession, or voluntarily return the Software to us.

    (c) Upon termination you will destroy all copies of the Software.

    (d) Otherwise, the restrictions on your rights to use the Software will expire upon expiration of the copyright to the Software.

    7. Miscellaneous Provisions.

    (a) This Agreement will be governed by and construed in accordance with the substantive laws of England whose courts shall have exclusive jurisdiction over all disputes which may arise between us.

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    SCHEDULE 1 Acknowledgments

    If you use FreeBody, you should reference the following papers in any publication:

    Cleather, D. J., & Bull, A. M. J. (2015). The development of a segment-based musculoskeletal model of the lower limb: Introducing FreeBody. Royal Society Open Science, 2, 140449. doi: 10.1098/rsos.140449

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